Investigating ways to eliminate HIV for better health outcomes
Official title: STudy of Acute HIV for investiGating Eradication Strategies (STAGES)
Funded at University of California, San Francisco · NIH-11118300 · Data updated 2026-11-12
This study is looking for ways to help people with HIV stay healthy without needing to take daily medication, by exploring how certain signals in the immune system can help reduce the virus in the body, and it invites patients to participate in trials to discover new treatment options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $794,045 |
| NIH project number | 1R56AI181653-01 |
| Project ID | NIH-11118300 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with acute HIV infection or those undergoing ART.
✕Less likely to help
Patients with chronic HIV infection who are not currently undergoing treatment may not benefit from this research.
What this research studies
This research focuses on finding methods to achieve long-term remission from HIV without the need for ongoing antiretroviral therapy (ART). It aims to understand how certain immune system signals, specifically class II cytokines, influence the decay of the HIV reservoir in the body. By studying different stages of HIV infection and treatment, the researchers hope to identify new therapeutic strategies that could lead to a cure. Patients may be involved in trials that explore these mechanisms and their effects on HIV control.
Why it matters
Potential benefit: If successful, this research could lead to a cure for HIV, allowing patients to live without the need for lifelong medication.
How similar studies have gone: Previous research has shown promise in understanding the role of immune signals in HIV control, but this specific approach is novel and aims to fill critical gaps in current knowledge.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Lee, Sulggi Angela — University of California, San Francisco
- Study coordinator: Lee, Sulggi Angela
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.