NIH-funded research NIH-funded research

Investigating ways to eliminate HIV for better health outcomes

Official title: STudy of Acute HIV for investiGating Eradication Strategies (STAGES)

Funded at University of California, San Francisco · NIH-11118300 · Data updated 2026-11-12

This study is looking for ways to help people with HIV stay healthy without needing to take daily medication, by exploring how certain signals in the immune system can help reduce the virus in the body, and it invites patients to participate in trials to discover new treatment options.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startAugust 1, 2024
Project endJuly 31, 2025
Funding year2024
Award (this year)$794,045
NIH project number1R56AI181653-01
Project IDNIH-11118300 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with acute HIV infection or those undergoing ART.

Less likely to help

Patients with chronic HIV infection who are not currently undergoing treatment may not benefit from this research.

What this research studies

This research focuses on finding methods to achieve long-term remission from HIV without the need for ongoing antiretroviral therapy (ART). It aims to understand how certain immune system signals, specifically class II cytokines, influence the decay of the HIV reservoir in the body. By studying different stages of HIV infection and treatment, the researchers hope to identify new therapeutic strategies that could lead to a cure. Patients may be involved in trials that explore these mechanisms and their effects on HIV control.

Why it matters

Potential benefit: If successful, this research could lead to a cure for HIV, allowing patients to live without the need for lifelong medication.

How similar studies have gone: Previous research has shown promise in understanding the role of immune signals in HIV control, but this specific approach is novel and aims to fill critical gaps in current knowledge.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Lee, Sulggi Angela — University of California, San Francisco
  • Study coordinator: Lee, Sulggi Angela

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.