Investigating the role of TSPAN2 in blood vessel diseases
Function and Regulation of TSPAN2 in Vascular Disease
This study is looking at a protein called TSPAN2 in blood vessel cells to see how it affects their behavior, which could help us find new ways to treat conditions like atherosclerosis and improve blood vessel health for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Augusta University NIH-funded |
| Lab location | 1 site (Augusta, United States) |
| Project ID | NIH-10543854 on NIH RePORTER |
What this research studies
This research focuses on understanding how TSPAN2, a specific protein found in vascular smooth muscle cells, influences the behavior of these cells in the context of vascular diseases like atherosclerosis. The study examines how TSPAN2 affects cell differentiation and migration, which are critical processes in maintaining healthy blood vessels. By analyzing data from various screenings and exploring the molecular mechanisms involved, the research aims to uncover potential therapeutic targets for treating vascular conditions. Patients may benefit from insights gained about how to better manage or prevent diseases related to blood vessels.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include adults with a history of vascular diseases such as atherosclerosis or those at risk due to genetic factors.
Not a fit: Patients with non-vascular related conditions or those under 21 years old may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for vascular diseases, improving patient outcomes and quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the role of transmembrane proteins in vascular diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Augusta, United States
- Augusta University — Augusta, United States (Active)
Researchers
- Principal investigator: Long, Xiaochun — Augusta University
- Study coordinator: Long, Xiaochun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.