Investigating the role of long noncoding RNAs in heart disease
Licensing LncRNAs in Atherosclerosis
This study is looking at how certain molecules called long noncoding RNAs might play a role in heart disease, specifically atherosclerosis, and it aims to find new ways to help improve heart health for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10745707 on NIH RePORTER |
What this research studies
This research explores how long noncoding RNAs (lncRNAs) contribute to the development of atherosclerosis, a major cause of cardiovascular disease. By examining both mouse and human models, the study aims to identify specific lncRNAs that influence lipid metabolism and may lead to new therapeutic strategies. The research team combines expertise in lncRNA biology and cardiovascular health to uncover potential treatments that could improve patient outcomes. Patients may benefit from insights gained about how lncRNAs affect heart health and the development of targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for or diagnosed with atherosclerosis or related cardiovascular diseases.
Not a fit: Patients with non-cardiovascular related health issues or those not affected by atherosclerosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that specifically target lncRNAs to reduce the risk and impact of atherosclerosis in patients.
How similar studies have performed: Other research has shown promising results in targeting lncRNAs for therapeutic purposes, suggesting that this approach may be viable.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Sallam, Tamer — University of California Los Angeles
- Study coordinator: Sallam, Tamer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.