Investigating the role of cellular aging in chronic diseases
Biological Analysis Core
This study is looking at how aging cells that stop dividing can affect our health, and it’s for anyone interested in understanding how these changes in our cells might be linked to diseases as we get older.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10909917 on NIH RePORTER |
What this research studies
This research focuses on understanding cellular senescence, a process where cells stop dividing and can contribute to various chronic diseases associated with aging. By utilizing advanced technologies, the team will analyze senescent cells at a molecular and single-cell level across different tissues, including lung, heart, and skin. The goal is to create detailed atlases that map the distribution and characteristics of these cells in individuals of various ages, from infants to older adults. This comprehensive approach aims to uncover the links between cellular aging and diseases like atherosclerosis and pulmonary fibrosis.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals experiencing chronic diseases associated with aging, particularly those under 55 years old.
Not a fit: Patients with acute conditions unrelated to aging or cellular senescence may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and potential treatments for chronic diseases related to aging.
How similar studies have performed: Previous research has shown promising results in understanding cellular senescence and its implications for chronic diseases, indicating that this approach has potential for significant findings.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Nixon, Andrew B. — Duke University
- Study coordinator: Nixon, Andrew B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.