Investigating the role of a protein in melanoma development and progression
Role of sirtuin 6 in melanoma development and progression
This study is looking at a protein called SIRT6 to see how it influences melanoma, a type of skin cancer, and aims to find new ways to treat patients who haven't had success with current treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wm S. Middleton Memorial Veterans Hosp NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10809642 on NIH RePORTER |
What this research studies
This research focuses on understanding how sirtuin 6 (SIRT6), a protein involved in various cellular processes, affects the development and progression of melanoma, a serious form of skin cancer. The study aims to explore the dual roles of SIRT6 in cancer, where it may either suppress or promote tumor growth depending on the context. By examining the mechanisms through which SIRT6 operates, researchers hope to identify new therapeutic targets for melanoma treatment. This could lead to more effective strategies for managing melanoma, especially in patients who have not responded well to existing therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with melanoma, particularly those who have not responded to current therapies.
Not a fit: Patients with non-melanoma skin cancers or those who have not been diagnosed with any form of skin cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for melanoma patients, improving outcomes and survival rates.
How similar studies have performed: Previous research has shown that targeting sirtuins can be effective in cancer treatment, suggesting that this approach may yield promising results.
Where this research is happening
Madison, United States
- Wm S. Middleton Memorial Veterans Hosp — Madison, United States (Active)
Researchers
- Principal investigator: Ahmad, Nihal — Wm S. Middleton Memorial Veterans Hosp
- Study coordinator: Ahmad, Nihal
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.