Investigating the link between Helicobacter infection and liver cancer risk in different racial groups in the U.S.
Helicobacter Infection and Liver Cancer Risk among African Americans andWhites in the United States
This study is looking at how infections from a bacteria called Helicobacter pylori might be linked to liver cancer, especially in African Americans and Whites, by analyzing blood samples to find out more about these infections and their role in liver cancer risk.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11070720 on NIH RePORTER |
What this research studies
This research focuses on understanding how infections from Helicobacter pylori and related species may contribute to the risk of developing liver cancer, particularly among African Americans and Whites. By analyzing data from a large cohort involved in the Liver Cancer Pooling Project, the study aims to identify potential risk factors associated with liver cancer that are not related to viral infections. The research will involve collecting and analyzing blood samples to assess the prevalence of Helicobacter infections and their possible role in liver cancer disparities. This comprehensive approach seeks to uncover new insights into liver cancer etiology and improve prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include African American and White individuals who may be at risk for liver cancer due to Helicobacter infections.
Not a fit: Patients who do not have Helicobacter infections or those with liver cancer caused solely by viral infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention of liver cancer, particularly in populations at higher risk.
How similar studies have performed: Previous research has indicated a potential link between Helicobacter infections and various cancers, suggesting that this approach may yield valuable insights, although it remains an area of ongoing investigation.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Zhang, Xuehong — Yale University
- Study coordinator: Zhang, Xuehong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.