Investigating the immune system in systemic lupus erythematosus
Principal Project
['FUNDING_OTHER'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-11080350
This study is looking at systemic lupus erythematosus (SLE) to find out what causes the disease and how to better track and tailor treatments for patients, especially those who developed it as children, by examining their immune responses and cell interactions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11080350 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding systemic lupus erythematosus (SLE), an autoimmune disease that causes inflammation and affects various organs. The study aims to identify key drivers of the disease and discover biomarkers that can help in monitoring and personalizing treatment for patients. By analyzing the immune responses, particularly in patients with childhood-onset SLE, the research seeks to stratify patients based on their specific disease characteristics, which could lead to more effective targeted therapies. The approach includes profiling immune cells and their interactions to better understand the disease's complexity.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults and children diagnosed with systemic lupus erythematosus, particularly those with childhood-onset SLE.
Not a fit: Patients with autoimmune conditions other than systemic lupus erythematosus may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for patients with systemic lupus erythematosus.
How similar studies have performed: Previous research has shown promise in understanding autoimmune diseases through similar approaches, indicating potential for success in this area.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PASCUAL, MARIA VIRGINIA — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: PASCUAL, MARIA VIRGINIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases, autoimmune disorder, autoimmunity disease