Investigating the genetics of bipolar disorder in Pakistan
Official title: The GEN-BLIP Study (GENetics of BipoLar Disorder In Pakistan)
Funded at Rutgers, the State Univ of N.j. · NIH-10841617 · Data updated 2026-11-12
This study is looking at the genes that might play a role in bipolar disorder, and it's inviting people with the condition to help researchers learn more so that better treatments can be developed in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers, the State Univ of N.j. NIH-funded |
| Lab location | 1 site (Piscataway, United States) |
| Project start | July 7, 2020 |
| Project end | April 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $618,774 |
| NIH project number | 5R01MH123775-05 |
| Project ID | NIH-10841617 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are individuals diagnosed with bipolar disorder in Pakistan.
✕Less likely to help
Patients with bipolar disorder outside of Pakistan or those without a genetic predisposition to the condition may not benefit from this research.
What this research studies
This research focuses on understanding the genetic factors that contribute to bipolar disorder, a mental health condition affecting approximately 1% of the global population. By collecting genetic samples from 10,000 individuals diagnosed with bipolar disorder and 2,000 control participants in Pakistan, the study aims to identify both rare and common genetic variants associated with the disorder. The research utilizes advanced genetic analysis techniques to uncover insights that could lead to more effective treatment strategies for bipolar disorder. Patients participating in this study will contribute to a larger understanding of the genetic basis of their condition, potentially benefiting future treatment options.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for bipolar disorder based on genetic insights.
How similar studies have gone: Previous research has shown success in identifying genetic factors in bipolar disorder through large-scale studies, indicating that this approach is promising.
Where this research is happening
-
Rutgers, the State Univ of N.j.
Piscataway, United States Active
Researchers
- Principal investigator: Knowles, James a — Rutgers, the State Univ of N.j.
- Study coordinator: Knowles, James a
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.