Investigating the effects of vagus nerve stimulation on various body systems.
REVEAL - Research Evaluating Vagal Excitation and Anatomical Linkages.
This study is looking at how vagus nerve stimulation (VNS) can help improve health in different areas of the body, and it's for people dealing with conditions like anxiety, depression, and gut issues, as it aims to find better treatment options through the experiences of over 140 participants.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10930816 on NIH RePORTER |
What this research studies
This research focuses on understanding how vagus nerve stimulation (VNS) affects multiple organ systems, including the autonomic nervous system, cardiovascular system, immune system, and metabolic system. By involving over 140 patients across eight major academic and medical institutions, the study aims to gather comprehensive data on the physiological responses to VNS. The research will optimize VNS settings for existing therapies and explore new therapeutic applications. Patient participation will help in collecting consistent data that could lead to improved treatment protocols for conditions like anxiety, depression, and gastrointestinal disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals suffering from anxiety disorders, depression, epilepsy, or gastrointestinal disorders who may benefit from vagus nerve stimulation.
Not a fit: Patients who do not have conditions related to the autonomic nervous system or those who are not candidates for vagus nerve stimulation may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to enhanced therapies for anxiety, depression, and other conditions treated with vagus nerve stimulation.
How similar studies have performed: Previous research has shown promising results with vagus nerve stimulation in treating various conditions, indicating that this approach has potential for significant advancements.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Osborn, John W — University of Minnesota
- Study coordinator: Osborn, John W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.