Investigating the effectiveness and safety of COVID-19 vaccines across different countries

International study on COVID-19 Vaccine to assess Immunogenicity, Reactogenicity and Efficacy (InVITE)

NIH-funded research Leidos Biomedical Research, INC. · NIH-10505920

This study is looking at how effective COVID-19 vaccines are and how long they protect people, and it's for anyone who has received the vaccine through national programs.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLeidos Biomedical Research, INC. NIH-funded
Lab location1 site (Frederick, United States)
Project IDNIH-10505920 on NIH RePORTER

What this research studies

This research focuses on understanding how well COVID-19 vaccines work and how long their effects last in people who receive them through national vaccination programs. It involves multiple international sites and examines various vaccination regimens, including both initial doses and booster shots. Patients participating in this study will help researchers gather important data on vaccine immunogenicity and the incidence of SARS-CoV-2 infections. The findings could provide valuable insights into vaccine performance in diverse populations.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have received a COVID-19 vaccine as part of their country's national vaccination program.

Not a fit: Patients who have not received a COVID-19 vaccine or those who are not part of the national vaccination programs may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance the understanding of COVID-19 vaccine effectiveness and inform future vaccination strategies.

How similar studies have performed: Other research has shown success in assessing vaccine efficacy and safety, making this approach a continuation of established methodologies.

Where this research is happening

Frederick, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions HTLV-III InfectionsHTLV-III-LAV InfectionsHuman T-Lymphotropic Virus Type III InfectionsHIV InfectionsInfection
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.