Investigating the biology and treatment of lupus affecting the skin and kidneys
Lupus Omics Cutaneous Kidney Investigative Team (LOCKIT)
This study is looking at how lupus affects the skin and kidneys by analyzing blood and tissue samples from patients, which will help us find early signs of kidney problems and improve treatments for managing lupus symptoms.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11017791 on NIH RePORTER |
What this research studies
This research focuses on understanding the complex biology and genetics of systemic lupus erythematosus (SLE), particularly how it affects the skin and kidneys. By utilizing advanced technologies, the team aims to analyze tissue and blood samples to uncover the differences in immune responses and disease progression. Patients will contribute samples that will help identify early signs of kidney disease and evaluate treatment responses, ultimately leading to better management of lupus symptoms. The study involves a collaborative effort among various specialists to address the unique challenges posed by this autoimmune disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with systemic lupus erythematosus, especially those showing symptoms related to the skin or kidneys.
Not a fit: Patients who do not have lupus or those with unrelated autoimmune conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and treatment strategies for patients with lupus, particularly those experiencing skin and kidney complications.
How similar studies have performed: Previous research initiatives like the Accelerating Medicine Partnership have shown success in understanding autoimmune diseases, indicating that this approach has potential for impactful results.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Buyon, Jill P — New York University School of Medicine
- Study coordinator: Buyon, Jill P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.