Investigating the biological differences in acute respiratory distress syndrome (ARDS)
Official title: Proteomic and metabolomic trajectories of ARDS molecular phenotypes
Funded at University of California, San Francisco · NIH-11053082 · Data updated 2026-11-12
This study is looking at the differences in blood proteins and substances in people with acute respiratory distress syndrome (ARDS) to find out if there are different types of ARDS that might need different treatments, helping doctors provide better care for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | December 20, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $200,502 |
| NIH project number | 1K23HL173659-01A1 |
| Project ID | NIH-11053082 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are diagnosed with acute respiratory distress syndrome.
✕Less likely to help
Patients with ARDS who are younger than 21 years old or those with other unrelated respiratory conditions may not benefit from this research.
What this research studies
This research focuses on understanding the molecular differences in patients with acute respiratory distress syndrome (ARDS) by analyzing proteins and metabolites in their blood. The study aims to identify distinct biological subtypes of ARDS, which may respond differently to treatments. By employing advanced computational methods and observational studies, the research seeks to enhance the understanding of ARDS and improve patient outcomes. Patients with ARDS will be monitored to gather data that could lead to more personalized treatment approaches.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments tailored to the specific biological subtype of ARDS a patient has.
How similar studies have gone: Previous research has shown promise in identifying biological subtypes of ARDS, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Alipanah-Lechner, Narges — University of California, San Francisco
- Study coordinator: Alipanah-Lechner, Narges
Related research
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-
Lipid-gene Profiles in Septic ARDS
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-
Improving blood vessel repair after pediatric ARDS
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-
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-
Leading causes of death in alcoholic ARDS patients using clinical data
This project uses big clinical data and AI to find the main factors that cause death in adults with ARDS who have alcohol use issues, aiming to improve understanding and care.
-
Targeting aging-related blood vessel injury to prevent ARDS in older lungs
Aims to find ways to protect lung blood vessels in older adults to prevent dangerous lung swelling (ARDS).
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.