Investigating new factors that cause blood vessel calcification
Official title: Novel Molecular Regulators of Vascular Calcification
Funded at Massachusetts General Hospital · NIH-10894597 · Data updated 2026-11-12
This study is looking at how certain genes and proteins cause blood vessel hardening, which can lead to heart problems and strokes, and it's for anyone interested in finding new ways to prevent or treat this condition.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $85,558 |
| NIH project number | 5F32HL164025-02 |
| Project ID | NIH-10894597 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for cardiovascular diseases, particularly those with a history of atherosclerosis or related conditions.
✕Less likely to help
Patients who do not have cardiovascular risk factors or existing vascular conditions may not benefit from this research.
What this research studies
This research focuses on understanding the molecular mechanisms behind vascular calcification, a process that contributes to serious cardiovascular diseases like coronary artery disease and stroke. The team is studying specific genes and proteins that influence how vascular smooth muscle cells change and contribute to calcification. By conducting various laboratory experiments, including in vitro and in vivo studies, they aim to identify potential targets for new therapies that could prevent or reduce vascular calcification in patients.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly reduce the risk of heart disease and stroke by preventing vascular calcification.
How similar studies have gone: Previous research has shown promise in targeting molecular regulators of vascular calcification, indicating that this approach could lead to meaningful advancements in treatment.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Lee, Sujin — Massachusetts General Hospital
- Study coordinator: Lee, Sujin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.