Investigating natural killer cells in lung injury
Natural killer cells in pulmonary ischemia-reperfusion injury
This study is looking at how certain immune cells called natural killer cells affect lung injuries that happen after a lack of blood flow, and it's designed for researchers who want to help improve treatments for people with lung problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Affairs Med Ctr San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10881733 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of natural killer (NK) cells in lung injuries caused by ischemia-reperfusion. The principal investigator, Dr. Daniel Calabrese, aims to explore how these immune cells contribute to acute lung injury and develop strategies to improve patient outcomes. The study involves both theoretical and practical training in immunology and bioinformatics, with the goal of laying the groundwork for future clinical trials targeting lung injury syndromes. A team of experienced mentors will guide the research to ensure robust scientific development.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing acute lung injury or conditions like acute respiratory distress syndrome (ARDS).
Not a fit: Patients with chronic lung diseases or those not experiencing acute lung injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve recovery from acute lung injuries and related conditions.
How similar studies have performed: Previous research has shown promise in understanding the role of NK cells in various lung conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
San Francisco, United States
- Veterans Affairs Med Ctr San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Calabrese, Daniel — Veterans Affairs Med Ctr San Francisco
- Study coordinator: Calabrese, Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.