Investigating myeloid cells and their role in atherosclerosis
Core C: Myeloid cell and atherosclerosis core
['FUNDING_P01'] · UNIVERSITY OF WASHINGTON · NIH-10874520
This study is looking at how certain immune cells affect the buildup of plaque in arteries, which can lead to heart problems, and it aims to find new ways to help people with cardiovascular issues by using special techniques to learn more about these plaques in mouse models.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-10874520 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how myeloid cells contribute to the development of atherosclerosis, a condition that can lead to cardiovascular diseases. By using advanced techniques such as histological staining, lesion size measurements, and gene expression analysis, the research aims to provide detailed insights into the characteristics of atherosclerotic lesions. The core facility will support various projects by offering expertise in analyzing data from mouse models, which can help in identifying potential therapeutic targets for patients with cardiovascular issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for atherosclerosis, including those with diabetes or other cardiovascular risk factors.
Not a fit: Patients with established atherosclerosis who are not participating in clinical trials related to this research may not receive direct benefits.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating atherosclerosis and related cardiovascular diseases.
How similar studies have performed: Previous research has shown promising results in understanding the role of myeloid cells in cardiovascular diseases, indicating that this approach has potential for success.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KANTER, JENNY E. — UNIVERSITY OF WASHINGTON
- Study coordinator: KANTER, JENNY E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Atherosclerotic Cardiovascular Disease