Investigating metabolism in critical illnesses like sepsis and ARDS
Translational Metabolomics in Critical Care
['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11011375
This study is looking at how the body changes during serious illnesses like sepsis and ARDS to find helpful markers that can predict how patients will do and improve their treatment.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-11011375 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the metabolic changes that occur during critical illnesses such as sepsis and Acute Respiratory Distress Syndrome (ARDS). By using advanced techniques in Translational Metabolomics, the study aims to identify biomarkers that can help predict patient outcomes and guide treatment. The research employs innovative animal models and clinical cohorts to validate findings, utilizing state-of-the-art analytical methods to analyze biological samples. This approach seeks to bridge the gap between laboratory discoveries and clinical applications, ultimately improving patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with sepsis or ARDS who are experiencing severe metabolic disturbances.
Not a fit: Patients with mild respiratory issues or those not diagnosed with sepsis or ARDS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and targeted therapies for patients suffering from sepsis and ARDS.
How similar studies have performed: Previous research has shown promise in using metabolomics to identify biomarkers in critical illnesses, indicating that this approach has potential for success.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: STRINGER, KATHLEEN A — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: STRINGER, KATHLEEN A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acute Respiratory Distress Syndrome, acute respiratory distress syndrome caused by sepsis, Adult Respiratory Distress Syndrome