Investigating kidney injury in children with chronic kidney disease

Acute Kidney Injury in Children with Chronic Kidney Disease

NIH-funded research Yale University · NIH-11045032

This study is looking at how to help kids with chronic kidney disease avoid sudden kidney problems and stay healthy by finding out what factors can be changed and how these issues affect their kidneys over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11045032 on NIH RePORTER

What this research studies

This research focuses on understanding acute kidney injury (AKI) in children who have chronic kidney disease (CKD). It aims to identify modifiable risk factors associated with AKI and explore how AKI impacts kidney health and function over time. By utilizing a large cohort of children with CKD, the study will conduct regular assessments of kidney function, blood pressure, and biomarkers to gain insights into kidney health. The goal is to develop strategies to prevent AKI and improve long-term outcomes for affected children.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who have been diagnosed with chronic kidney disease.

Not a fit: Patients who do not have chronic kidney disease or are outside the age range of 0-11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and management strategies for acute kidney injury in children with chronic kidney disease.

How similar studies have performed: Previous research has shown success in understanding kidney health in pediatric populations, but this specific focus on AKI in children with CKD is relatively novel.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions acute kidney injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.