Investigating kidney injury in children with chronic kidney disease
Official title: Acute Kidney Injury in Children with Chronic Kidney Disease
Funded at Yale University · NIH-11045032 · Data updated 2026-11-12
This study is looking at how to help kids with chronic kidney disease avoid sudden kidney problems and stay healthy by finding out what factors can be changed and how these issues affect their kidneys over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | May 5, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $334,046 |
| NIH project number | 5R01DK135650-03 |
| Project ID | NIH-11045032 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who have been diagnosed with chronic kidney disease.
✕Less likely to help
Patients who do not have chronic kidney disease or are outside the age range of 0-11 years may not benefit from this research.
What this research studies
This research focuses on understanding acute kidney injury (AKI) in children who have chronic kidney disease (CKD). It aims to identify modifiable risk factors associated with AKI and explore how AKI impacts kidney health and function over time. By utilizing a large cohort of children with CKD, the study will conduct regular assessments of kidney function, blood pressure, and biomarkers to gain insights into kidney health. The goal is to develop strategies to prevent AKI and improve long-term outcomes for affected children.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and management strategies for acute kidney injury in children with chronic kidney disease.
How similar studies have gone: Previous research has shown success in understanding kidney health in pediatric populations, but this specific focus on AKI in children with CKD is relatively novel.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Greenberg, Jason Henry — Yale University
- Study coordinator: Greenberg, Jason Henry
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.