Investigating kidney injury and repair mechanisms in aging and disease
Official title: BLR&D Research Career Scientist Award Application
Funded at Charlie Norwood VA Medical Center · NIH-11105916 · Data updated 2026-11-12
This study is looking at how kidney injuries happen and how we can help them heal, especially for older adults and those with diabetes or cancer, to find better ways to keep kidneys healthy and recover from damage.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Charlie Norwood VA Medical Center NIH-funded |
| Lab location | 1 site (Augusta, United States) |
| Project start | April 1, 2020 |
| Project end | March 30, 2027 |
| Funding year | 2025 |
| NIH project number | 5IK6BX005236-06 |
| Project ID | NIH-11105916 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include older adults and individuals with diabetes or those undergoing cancer therapies who are at risk for kidney injuries.
✕Less likely to help
Patients with chronic kidney disease or those not experiencing acute kidney injuries may not benefit from this research.
What this research studies
This research focuses on understanding how kidney injuries occur and how they can be repaired, particularly in older adults and those with conditions like diabetes or undergoing cancer treatment. The principal investigator, Dr. Zheng Dong, is exploring the roles of mitochondria, metabolism, and cellular processes like autophagy in kidney health. By studying these mechanisms, the research aims to identify new therapeutic strategies that could improve kidney function and recovery after injury. Patients may benefit from insights gained into how to better manage kidney health and prevent further damage.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve kidney recovery and function in patients with acute kidney injuries.
How similar studies have gone: Previous research has shown promising results in understanding kidney injury mechanisms, suggesting that this approach could lead to significant advancements in treatment.
Where this research is happening
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Charlie Norwood VA Medical Center
Augusta, United States Active
Researchers
- Principal investigator: Dong, Zheng — Charlie Norwood VA Medical Center
- Study coordinator: Dong, Zheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.