Investigating immune and metabolic factors in Coccidioides infections
Immune and metabolic correlates of Coccidioides disease spectrum and outcomes
This study is looking at how changes in the immune system and metabolism can influence how severe Valley Fever is for patients, and it aims to find patterns in blood samples that could help doctors make better treatment choices.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11004156 on NIH RePORTER |
What this research studies
This research focuses on understanding how the immune system and metabolic changes affect the severity of Coccidioides infections, commonly known as Valley Fever. By analyzing blood samples and other biological markers from patients, the researchers aim to identify patterns that predict disease outcomes and therapeutic responses. The study will utilize a combination of clinical data, immune response assessments, and metabolic profiling to uncover the mechanisms behind the disease's varying severity. Ultimately, this research seeks to develop a prognostic biosignature that can help guide treatment decisions for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Coccidioides infections, particularly those experiencing acute or chronic pulmonary symptoms.
Not a fit: Patients who do not have Coccidioides infections or those with unrelated pulmonary conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for patients suffering from Coccidioides infections.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for infectious diseases, suggesting that this approach may yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Dandekar, Satya — University of California, San Francisco
- Study coordinator: Dandekar, Satya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.