Investigating how toxicants and inflammation affect metabolic health in mid-life women
Metabolic Health Risk Among Mid-Life Women: The Roles of Toxicants, Inflammation, and Epigenetics
This study is looking at how everyday chemicals, like those found in some plastics and personal care products, might affect the health of women going through menopause, especially regarding issues like weight gain and inflammation, and how lifestyle choices like diet and exercise can help improve their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10887437 on NIH RePORTER |
What this research studies
This research focuses on understanding the impact of environmental toxicants, specifically phthalates and phenols, on metabolic health among women in mid-life. It examines how these chemicals, often found in everyday products, may contribute to metabolic syndrome and inflammation during the peri-menopausal period. The study aims to explore the interactions between these toxicants and lifestyle factors such as diet, sleep, and physical activity, as well as the potential epigenetic changes that may occur. By identifying these relationships, the research seeks to provide insights into how short-term changes in health behaviors can mitigate risks associated with metabolic syndrome.
Who could benefit from this research
Good fit: Ideal candidates for this research are mid-life women experiencing hormonal changes associated with menopause and who may be exposed to environmental toxicants.
Not a fit: Patients who are not in the mid-life age range or who do not have exposure to the identified toxicants may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for reducing metabolic syndrome risk among mid-life women, enhancing their overall health and well-being.
How similar studies have performed: Previous studies have indicated a link between environmental toxicants and metabolic health, but this research aims to fill critical gaps by examining lifestyle interactions, making it a novel approach.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Peterson, Karen Eileen — University of Michigan at Ann Arbor
- Study coordinator: Peterson, Karen Eileen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.