Investigating how statin medications may reduce suicide risk in US Veterans with inflammation-related conditions.
Official title: Suicide risk modification by statin prescriptions in US Veterans with common inflammation-mediated clinical conditions- a controlled, quasi-randomized epidemiological approach
Funded at Baltimore VA Medical Center · NIH-11044037 · Data updated 2026-11-12
This study is looking at whether statin medications, which are usually taken for heart health, can also help reduce the risk of suicide in US Veterans who have inflammation-related health issues, like traumatic brain injuries or autoimmune disorders, by comparing different ways of taking the medication.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baltimore VA Medical Center NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| NIH project number | 5I01CX002259-03 |
| Project ID | NIH-11044037 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include US Veterans with a history of traumatic brain injury or inflammation-mediated medical conditions.
✕Less likely to help
Patients without a history of inflammation-related conditions or those not taking statins may not benefit from this research.
What this research studies
This research explores the potential of statin medications, commonly used for heart health, to also lower suicide risk among US Veterans suffering from inflammation-related conditions. By analyzing electronic medical records, the study aims to understand how factors like traumatic brain injury and autoimmune disorders interact with suicide risk. The research will compare the effects of continuous versus intermittent statin treatment on mental health outcomes. Ultimately, it seeks to identify which Veterans are most likely to benefit from these treatments.
Why it matters
Potential benefit: If successful, this research could lead to new preventative strategies for reducing suicide risk in Veterans.
How similar studies have gone: Previous research has shown promising results in using statins for various health benefits, but this specific approach to suicide prevention is novel.
Where this research is happening
-
Baltimore VA Medical Center
Baltimore, United States Active
Researchers
- Principal investigator: Postolache, Teodor T — Baltimore VA Medical Center
- Study coordinator: Postolache, Teodor T
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.