Investigating how small RNA modifications affect glioma
The role of small RNA modifications in glioma
['FUNDING_OTHER'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-10879074
This study is looking at tiny pieces of RNA in brain cancer called glioma to see how changes in them might affect the cancer's growth and behavior, with the hope of finding new ways to diagnose or treat the disease.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded) |
| Locations | 1 site (BIRMINGHAM, UNITED STATES) |
| Trial ID | NIH-10879074 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the role of small non-coding RNAs, particularly tRNA-related fragments, in glioma, a type of brain cancer. The study aims to explore how modifications to these small RNAs can influence gene expression and contribute to the development and progression of gliomas. By analyzing glioma cell lines and patient samples, the research seeks to identify specific small RNA modifications that may serve as potential biomarkers or therapeutic targets. The approach includes detailed examinations of the biological functions of these modifications and their impact on cancer cell behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with glioma or glioblastoma, particularly those who may benefit from novel therapeutic strategies.
Not a fit: Patients with other types of cancer or those without glioma may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and potential treatments for glioma patients, improving outcomes and survival rates.
How similar studies have performed: While the specific focus on small RNA modifications in glioma is relatively novel, similar approaches in other cancers have shown promising results.
Where this research is happening
BIRMINGHAM, UNITED STATES
- UNIVERSITY OF ALABAMA AT BIRMINGHAM — BIRMINGHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SU, ZHANGLI — UNIVERSITY OF ALABAMA AT BIRMINGHAM
- Study coordinator: SU, ZHANGLI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brain Cancer