Investigating how sleep affects memory and aging
Official title: Probing sleep and memory as targets for rejuvenation
Funded at University of California, San Francisco · NIH-11047469 · Data updated 2026-11-12
This study is looking at how sleep affects memory as we get older, and it aims to find ways to improve sleep to help boost memory in older adults.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | November 15, 2024 |
| Project end | October 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $442,938 |
| NIH project number | 1R21AG091327-01 |
| Project ID | NIH-11047469 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults experiencing memory decline or cognitive impairment.
✕Less likely to help
Patients who are not experiencing age-related cognitive decline or who have other neurological disorders may not benefit from this research.
What this research studies
This research explores the relationship between sleep and memory, particularly how these processes change as we age. It aims to understand the mechanisms behind age-related memory decline and how improving sleep could potentially reverse this decline. By studying the effects of sleep on memory consolidation and synaptic changes in both nematodes and mammals, the researchers hope to identify ways to enhance memory function in older adults. The project will involve detailed examinations of sleep patterns and their impact on memory formation in aging subjects.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or reversing memory decline associated with aging.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between sleep and memory, indicating that this approach has potential for success.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: L 'Etoile, Noelle D — University of California, San Francisco
- Study coordinator: L 'Etoile, Noelle D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.