Investigating how SGLT2 inhibitors affect heart health in women with HIV

Who could benefit from this research

What this research studies

This research focuses on women living with HIV who are at a higher risk of heart attacks. It aims to explore how a specific class of medications, known as SGLT2 inhibitors, can improve heart function and reduce risks associated with type 2 myocardial infarction. The study will involve a randomized controlled trial where participants will receive either the medication or a placebo, and their heart health will be monitored using advanced imaging techniques. By understanding the effects of these medications, the research seeks to identify new ways to protect heart health in this vulnerable population.

Why it matters

Where this research is happening

• Massachusetts General Hospital
  Boston, United States Active

Researchers

• Principal investigator: Zanni, Markella V. — Massachusetts General Hospital
• Study coordinator: Zanni, Markella V.

Related research

Other NIH-funded projects on the same topics.

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  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11417336

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.