Investigating how mood affects learning and attention in people with mood disorders

A Computational Psychiatry Investigation of the effects of Mood on Reward Learning and Attention

['FUNDING_R01'] · PRINCETON UNIVERSITY · NIH-10656297

This study is looking at how mood affects learning and attention in people with mood disorders like bipolar disorder and depression, and it invites participants to help researchers find out what makes these conditions different from each other.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorPRINCETON UNIVERSITY (nih funded)
Locations1 site (Princeton, UNITED STATES)
Trial IDNIH-10656297 on ClinicalTrials.gov

What this research studies

This research explores the complex relationship between mood, reward learning, and attention, particularly in individuals with mood disorders like bipolar disorder and major depression. By using computational models and methodologies, the study aims to understand how mood influences cognitive processes and how these interactions can differ between various mood disorders. Participants may engage in human studies and contribute to large-scale online data collection to help uncover these patterns. The goal is to identify distinct behavioral and neural markers that differentiate bipolar disorder from major depression.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with bipolar disorder or major depression.

Not a fit: Patients without mood disorders or those with other unrelated psychiatric conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for mood disorders, enhancing patient outcomes.

How similar studies have performed: Previous research has shown promise in using computational models to study mood disorders, indicating that this approach could yield valuable insights.

Where this research is happening

Princeton, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Bipolar Disorder, bipolar affective disorder, bipolar disease, manic depressive disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.