Investigating how metal exposure from e-cigarettes affects heart health.
Metal Exposure and Early Cardiovascular Risk in Adult E-Cigarette Users
['FUNDING_R01'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-10845680
This study is looking at how using e-cigarettes might affect your heart health by checking for harmful metals in the vapor and seeing how they relate to things like blood pressure and heart artery health, and it's open to adults aged 18 to 50 who use tobacco in different ways.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10845680 on ClinicalTrials.gov |
What this research studies
This research examines the health effects of electronic cigarette (e-cig) use, particularly focusing on the exposure to toxic metals like lead and nickel found in e-cig aerosols. The study will assess the relationship between e-cigarette use and cardiovascular health by evaluating factors such as coronary artery calcification, blood pressure, and inflammation over a period of 1.5 years. Participants will include diverse adults aged 18 to 50, with varying backgrounds in tobacco use, and will be monitored at three different time points to gather comprehensive data on metal exposure and cardiovascular effects.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 18 to 50 who use e-cigarettes, including both current and former smokers, as well as those who have never smoked tobacco.
Not a fit: Patients who do not use e-cigarettes or tobacco products may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of the cardiovascular risks associated with e-cigarette use, potentially informing public health guidelines and individual choices.
How similar studies have performed: Previous research has indicated concerning levels of toxic metals in e-cig aerosols, suggesting that this investigation builds on existing findings but explores new associations with cardiovascular health.
Where this research is happening
NEW YORK, UNITED STATES
- COLUMBIA UNIVERSITY HEALTH SCIENCES — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NAVAS-ACIEN, ANA — COLUMBIA UNIVERSITY HEALTH SCIENCES
- Study coordinator: NAVAS-ACIEN, ANA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Atherosclerotic Cardiovascular Disease, atherosclerotic disease, atherosclerotic vascular disease