Investigating how local sleep affects mental fatigue
Local sleep and mental fatigue
This study is looking at how not getting enough sleep and heavy studying can make you feel tired and less sharp mentally, and it aims to find out how certain brain cells are involved in this process, so we can learn how to help improve sleep and reduce mental fatigue for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11045769 on NIH RePORTER |
What this research studies
This research explores the relationship between local sleep and mental fatigue, particularly how sleep deprivation and intense learning can lead to feelings of exhaustion and cognitive impairment. It aims to understand the neural mechanisms behind mental fatigue by examining the activity of specific brain cells during wakefulness. The study will involve both animal models and human participants to identify how local neuronal inactivity can impact cognitive performance. By improving our understanding of these processes, the research seeks to find ways to alleviate mental fatigue through better sleep quality.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing mental fatigue due to neurological or psychiatric disorders, as well as healthy individuals who have undergone intense learning or sleep deprivation.
Not a fit: Patients with stable mental health and no history of sleep disorders or cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving mental fatigue in patients with neurological and psychiatric conditions.
How similar studies have performed: Previous research has shown promising results in understanding the effects of sleep on cognitive function, suggesting that this approach could yield valuable insights.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Cirelli, Chiara — University of Wisconsin-Madison
- Study coordinator: Cirelli, Chiara
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.