Investigating how lipids are processed in the body using advanced mass spectrometry techniques.
Measuring Lipid Flux By Ultra High Resolution Mass Spectrometry
This study is working on new ways to track how fats are made and changed in the body, which can help us learn more about diseases like heart disease, cancer, and diabetes, so we can better understand these conditions in people without needing to rely as much on animal testing.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10911856 on NIH RePORTER |
What this research studies
This research focuses on developing innovative tools to measure how lipids are synthesized and remodeled in the body, which is crucial for understanding various diseases like atherosclerosis, cancer, and diabetes. By utilizing a state-of-the-art ultra-high resolution mass spectrometer, the study aims to enhance the accuracy and sensitivity of lipid metabolism analysis. This approach could allow researchers to directly observe lipid changes in patients, potentially reducing reliance on animal models. The ultimate goal is to improve our understanding of metabolic disorders and their progression.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions such as atherosclerosis, diabetes, or other metabolic disorders linked to lipid metabolism.
Not a fit: Patients without any lipid metabolism disorders or those not affected by the diseases being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic and treatment options for patients suffering from lipid-related diseases.
How similar studies have performed: Previous research has shown promise in using advanced mass spectrometry techniques for studying lipid metabolism, indicating a potential for success in this novel approach.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Mitsche, Matthew Alvin — Ut Southwestern Medical Center
- Study coordinator: Mitsche, Matthew Alvin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.