Investigating how insomnia and brain injuries affect treatment responses
Molecular Mechanisms Associated with Insomnia and Response to Cognitive Behavioral Therapy for Insomnia
This study is looking at how insomnia affects active-duty military members who have had a traumatic brain injury, and how well a specific therapy for insomnia works for them, by checking their health before and after treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | South Texas Veterans Health Care System NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-10856912 on NIH RePORTER |
What this research studies
This research explores the relationship between insomnia and traumatic brain injury (TBI), particularly focusing on how these conditions impact the effectiveness of Cognitive Behavioral Therapy for Insomnia (CBTi). It involves a cohort of active-duty personnel with insomnia, who will be categorized based on their TBI status. Participants will undergo clinical assessments and blood tests before and after a series of CBTi sessions to evaluate changes in their condition and treatment response. The goal is to understand the molecular mechanisms that may influence treatment outcomes for those with insomnia and TBI.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who experience insomnia, particularly those with a history of traumatic brain injury.
Not a fit: Patients without insomnia or those who do not have a history of traumatic brain injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for insomnia in patients with traumatic brain injuries.
How similar studies have performed: Previous research has indicated that addressing sleep disturbances in patients with TBI can lead to improved outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
San Antonio, United States
- South Texas Veterans Health Care System — San Antonio, United States (Active)
Researchers
- Principal investigator: Mithani, Sara — South Texas Veterans Health Care System
- Study coordinator: Mithani, Sara
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.