Investigating how hormonal changes affect mucus secretion in the endocervix for drug development
A multi-disciplinary approach to uncover novel insights of endocervical mucus secretion for future drug discovery
This study is looking at how hormones affect the mucus in the cervix, with the goal of finding new ways to help with fertility or contraception that don’t rely on hormones, so it could be helpful for anyone trying to understand their reproductive health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11140909 on NIH RePORTER |
What this research studies
This research aims to explore the cells and pathways that influence changes in endocervical mucus due to hormonal fluctuations. By understanding these mechanisms, the study seeks to develop new, non-hormonal treatments that could either inhibit or enhance fertility. The research will utilize advanced methodologies to analyze mucus properties and their implications for reproductive health. Patients may benefit from insights that could lead to improved contraceptive methods or fertility treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing fertility issues or those seeking non-hormonal contraceptive options.
Not a fit: Patients who are not affected by hormonal changes or those not seeking fertility-related treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative non-hormonal therapies for contraception and fertility enhancement.
How similar studies have performed: Previous research in related fields, particularly in airway mucus studies, has shown promising advancements, suggesting potential for success in this novel approach.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Han, Leo Liu — Oregon Health & Science University
- Study coordinator: Han, Leo Liu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.