Investigating how exercise affects stress resilience differently in men and women
Sex and circuit-specific determinants of exercise-induced stress resilience
['FUNDING_R01'] · UNIVERSITY OF COLORADO DENVER · NIH-11086788
This study is looking at how exercise helps men and women handle stress differently, especially focusing on women who often deal with stress-related mood and anxiety issues, to find out what makes exercise work better for them.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-11086788 on ClinicalTrials.gov |
What this research studies
This research explores the differences in how exercise influences stress resilience in men and women, particularly focusing on women who are more prone to stress-related mood and anxiety disorders. The study examines the mechanisms behind the stress-buffering effects of exercise, using animal models to understand how exercise impacts brain circuits and serotonin activity. By analyzing various biological and behavioral responses, the research aims to identify specific factors that enhance stress resistance in females compared to males.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing stress-related mood and anxiety disorders.
Not a fit: Patients who do not identify as female or those not experiencing stress-related mood or anxiety disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted exercise-based interventions that improve mental health outcomes for women facing stress-related disorders.
How similar studies have performed: While the specific focus on sex differences in exercise-induced stress resilience is novel, previous research has shown that exercise can have significant mental health benefits.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GREENWOOD, BEN N — UNIVERSITY OF COLORADO DENVER
- Study coordinator: GREENWOOD, BEN N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Affective Disorders, Anxiety Disorders