Investigating how environmental factors affect autoimmune diseases in Native American communities
Environmental Influences Driving Autoimmunity and Autoimmune Disease in Tribal Members
['FUNDING_OTHER'] · CHEROKEE NATION · NIH-10912534
This study is looking at how the environment affects autoimmune diseases in Native American communities, especially in the Cherokee Nation, to find better ways to diagnose and treat these conditions, while also checking how COVID-19 might change things for those already dealing with autoimmune issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CHEROKEE NATION (nih funded) |
| Locations | 1 site (TAHLEQUAH, UNITED STATES) |
| Trial ID | NIH-10912534 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the unique environmental influences that contribute to autoimmune diseases among Native American populations, particularly in the Cherokee Nation. It aims to identify specific autoantibodies and cytokine signatures that differ from those found in other racial groups, which complicates diagnosis and treatment in primary care settings. The study also explores the impact of COVID-19 on autoantibody production, which may exacerbate existing autoimmune conditions. By collaborating with local communities, the research seeks to improve diagnostic and treatment strategies tailored to the needs of tribal members.
Who could benefit from this research
Good fit: Ideal candidates for this research include Native American individuals experiencing symptoms of autoimmune diseases or those with a family history of such conditions.
Not a fit: Patients who do not identify as Native American or who do not have autoimmune disease symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and effective treatments for autoimmune diseases in Native American populations.
How similar studies have performed: Previous research has shown that understanding unique autoantibody profiles in specific populations can lead to improved healthcare outcomes, suggesting this approach has potential for success.
Where this research is happening
TAHLEQUAH, UNITED STATES
- CHEROKEE NATION — TAHLEQUAH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JAMES, JUDITH A — CHEROKEE NATION
- Study coordinator: JAMES, JUDITH A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases