Investigating how certain transport proteins affect inflammation and autoimmune diseases
Chemoproteomic-Enabled Strategy to Study SLC Transporter Roles in Inflammation
['FUNDING_R01'] · SCRIPPS RESEARCH INSTITUTE, THE · NIH-10873912
This study is looking at how certain proteins in our immune system affect inflammation and autoimmune diseases like lupus and Crohn's, with the hope of finding new ways to help people manage these conditions better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SCRIPPS RESEARCH INSTITUTE, THE (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10873912 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the role of specific transport proteins in the immune system, particularly how they contribute to inflammation and autoimmune diseases like lupus and Crohn's disease. By examining the mechanisms through which these proteins operate, the study aims to identify potential therapeutic targets that could help regulate immune responses. The approach involves using advanced chemoproteomic techniques to analyze the interactions and functions of these proteins in immune cells. Patients may benefit from insights gained that could lead to new treatments for autoimmune conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with autoimmune diseases such as systemic lupus erythematosus or Crohn's disease.
Not a fit: Patients with non-autoimmune conditions or those not affected by inflammation may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that better manage or even prevent autoimmune diseases.
How similar studies have performed: Previous research has shown promise in targeting immune pathways for treating autoimmune diseases, indicating that this approach could be beneficial.
Where this research is happening
LA JOLLA, UNITED STATES
- SCRIPPS RESEARCH INSTITUTE, THE — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PARKER, CHRISTOPHER G — SCRIPPS RESEARCH INSTITUTE, THE
- Study coordinator: PARKER, CHRISTOPHER G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases