Investigating how C1QL3 affects brain cell connections
The Molecular Role of C1QL3 and its Binding Partners in Synaptic Regulation
This study is looking at how a protein called C1QL3 helps brain cells connect with each other, which is important for conditions like ADHD and autism, to find new ways to improve treatment for these disorders.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Sch of Med/dnt NIH-funded |
| Lab location | 1 site (Farmington, United States) |
| Project ID | NIH-10997468 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of a protein called C1QL3 in regulating connections between brain cells, which are crucial for proper brain function. By studying how C1QL3 interacts with other proteins at synapses, the research aims to uncover the mechanisms behind synaptic dysfunction in neuropsychiatric disorders like ADHD and autism. The approach involves advanced microscopy techniques to visualize these interactions in neuron cultures, providing insights that could lead to new therapeutic strategies for these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with neuropsychiatric disorders such as ADHD or autism.
Not a fit: Patients with neuropsychiatric disorders not related to synaptic dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new treatments for neuropsychiatric disorders that improve patients' quality of life.
How similar studies have performed: Previous research has shown promise in targeting synaptic adhesion molecules for therapeutic interventions in neuropsychiatric disorders, indicating a potential for success in this area.
Where this research is happening
Farmington, United States
- University of Connecticut Sch of Med/dnt — Farmington, United States (Active)
Researchers
- Principal investigator: Caro, Keaven Delwyn Jacob — University of Connecticut Sch of Med/dnt
- Study coordinator: Caro, Keaven Delwyn Jacob
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.