Investigating how aspirin can prevent colorectal cancer based on individual factors.
Precision Prevention Research Program
This study is looking at how aspirin might help prevent colorectal cancer by considering things like your age and gut health, and it aims to create personalized prevention plans that work best for you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10920368 on NIH RePORTER |
What this research studies
This research focuses on understanding how aspirin can be used to prevent colorectal cancer (CRC) by examining individual differences such as age and gut microbiome. The approach involves analyzing data from various sources, including population studies and clinical cohorts, to identify molecular markers that influence the effectiveness of aspirin. By developing personalized prevention strategies, the research aims to move beyond a one-size-fits-all approach to cancer prevention. Patients may be involved in clinical trials that assess the impact of aspirin on CRC risk based on their unique biological characteristics.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for colorectal cancer, particularly those with specific age and biological factors that may influence aspirin's effectiveness.
Not a fit: Patients who do not have risk factors for colorectal cancer or those who are not eligible for aspirin therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized strategies for preventing colorectal cancer.
How similar studies have performed: Previous research has shown promising results in using aspirin for cancer prevention, but this approach of precision prevention based on individual factors is relatively novel.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Chan, Andrew T — Massachusetts General Hospital
- Study coordinator: Chan, Andrew T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.