Investigating how anandamide affects blood pressure control
Official title: Anandamide in blood pressure control
Funded at University of Colorado Denver · NIH-11078318 · Data updated 2026-11-12
This study is looking at how a natural substance in your body called anandamide affects blood pressure, especially for people with high blood pressure, to find new ways to help manage it better and keep your heart healthy.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | May 1, 2024 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $94,500 |
| NIH project number | 5R21HL169709-02 |
| Project ID | NIH-11078318 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who are experiencing hypertension or related cardiovascular issues.
✕Less likely to help
Patients with stable blood pressure and no history of hypertension or cardiovascular disease may not benefit from this research.
What this research studies
This research explores the role of anandamide, a naturally occurring compound in the body, in regulating blood pressure, particularly in individuals with hypertension. The study aims to understand how the endocannabinoid system, which includes anandamide, interacts with the body's mechanisms for controlling blood pressure and how this may lead to adverse effects in patients undergoing treatment for hypertension. By examining the relationship between anandamide levels and blood pressure responses, the research seeks to identify potential new therapeutic strategies for managing hypertension and reducing the risk of cardiovascular events.
Why it matters
Potential benefit: If successful, this research could lead to improved blood pressure management strategies that minimize adverse effects for patients with hypertension.
How similar studies have gone: Previous studies have shown promising results regarding the role of the endocannabinoid system in blood pressure regulation, indicating that this approach may yield valuable insights.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Klawitter, Jelena — University of Colorado Denver
- Study coordinator: Klawitter, Jelena
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.