Investigating how a specific protein affects heart and kidney health
Role of SuPAR in the Intersection between Cardiovascular and Kidney Disease
This study is looking at a protein called suPAR to see how it affects heart and kidney health, and it’s for patients who want to help researchers find out if suPAR can be used to predict disease risk and develop new treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Med Br Galveston NIH-funded |
| Lab location | 1 site (Galveston, United States) |
| Project ID | NIH-11180738 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of a protein called suPAR in the relationship between cardiovascular disease and chronic kidney disease. It aims to explore how suPAR, produced by certain immune cells, influences kidney function and cardiovascular health. By examining the levels of suPAR in patients, the study seeks to identify its potential as a biomarker for disease risk and a target for new therapies. Patients may be involved in providing samples and health data to help uncover these connections.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic kidney disease who may also be at risk for cardiovascular disease.
Not a fit: Patients without chronic kidney disease or those who do not have cardiovascular risk factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve heart and kidney health for patients with chronic kidney disease.
How similar studies have performed: Previous research has shown promise in targeting similar inflammatory pathways, suggesting potential for success in this area.
Where this research is happening
Galveston, United States
- University of Texas Med Br Galveston — Galveston, United States (Active)
Researchers
- Principal investigator: Hayek, Salim — University of Texas Med Br Galveston
- Study coordinator: Hayek, Salim
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.