Investigating how a specific molecule affects blood vessel regulation in women with endometriosis
Official title: The Role of Thromboxane A2 in Vascular Regulation in Women with Endometriosis
Funded at Pennsylvania State University, the · NIH-11006255 · Data updated 2026-11-12
This study is looking at how a substance called thromboxane A2 affects blood vessels in women with endometriosis, to help find ways to improve heart health for those who might be at risk for cardiovascular problems.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $48,259 |
| NIH project number | 5F31HL170616-02 |
| Project ID | NIH-11006255 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women diagnosed with endometriosis who may be at risk for cardiovascular disease.
✕Less likely to help
Patients without a diagnosis of endometriosis or those who do not have cardiovascular risk factors may not benefit from this research.
What this research studies
This research focuses on understanding the role of thromboxane A2 (TxA2) in regulating blood vessels in women suffering from endometriosis, a condition that can increase the risk of cardiovascular disease. The study will explore how TxA2 affects blood vessel function and contributes to cardiovascular issues by examining its interaction with vascular smooth muscle and endothelial cells. By analyzing these mechanisms, the research aims to uncover potential pathways that could lead to improved cardiovascular health for affected women.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of cardiovascular risks in women with endometriosis.
How similar studies have gone: Previous research has indicated that understanding the role of inflammatory markers in cardiovascular disease can lead to significant advancements in treatment, suggesting this approach has potential for success.
Where this research is happening
-
Pennsylvania State University, the
University Park, United States Active
Researchers
- Principal investigator: Williams, Auni — Pennsylvania State University, the
- Study coordinator: Williams, Auni
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.