Investigating heart and kidney health in people with type 1 diabetes
Early myocardial remodeling and progressive kidney function decline in type 1 diabetes
This study is looking at how early heart changes might be linked to kidney problems in people with type 1 diabetes, and it’s for anyone experiencing kidney issues, as it could help improve how we monitor and treat these conditions together.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Joslin Diabetes Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10984998 on NIH RePORTER |
What this research studies
This research focuses on understanding how early changes in heart structure and function are related to kidney function decline in individuals with type 1 diabetes. By using advanced cardiac imaging techniques and biomarker analysis, the study aims to identify the initial signs of heart problems, specifically diabetic cardiomyopathy, in patients experiencing kidney issues. Participants will include those with varying degrees of kidney function decline, allowing researchers to compare heart health across different groups. The findings could lead to better monitoring and treatment strategies for patients with type 1 diabetes and kidney disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with type 1 diabetes who are experiencing varying degrees of kidney function decline.
Not a fit: Patients with type 1 diabetes who have stable kidney function and do not show signs of kidney decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and treatment of heart problems in patients with type 1 diabetes, potentially reducing cardiovascular complications.
How similar studies have performed: Previous research has indicated a connection between kidney function decline and heart health in diabetes, suggesting that this approach may yield valuable insights.
Where this research is happening
Boston, United States
- Joslin Diabetes Center — Boston, United States (Active)
Researchers
- Principal investigator: Doria, Alessandro — Joslin Diabetes Center
- Study coordinator: Doria, Alessandro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.