Investigating genetic factors linked to schizophrenia and bipolar disorder
Multiethnic genomic epigenomic and transcriptomic fine-mapping and functional validation analysis of schizophrenia and bipolar disorder risk loci
This study is looking at the genes that might play a role in schizophrenia and bipolar disorder to help us understand how these conditions develop, which could lead to better treatments for those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10974473 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic and molecular mechanisms behind schizophrenia and bipolar disorder, which are serious mental illnesses affecting many individuals. By analyzing genetic data from diverse populations, the study aims to identify specific genetic variants that contribute to these disorders. The researchers will use advanced techniques to map these variants and explore their functional roles in brain tissue. This comprehensive approach could lead to a better understanding of how these conditions develop and potentially inform future treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with schizophrenia or bipolar disorder, particularly those of diverse ethnic backgrounds.
Not a fit: Patients with other psychiatric disorders or those without a diagnosis of schizophrenia or bipolar disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and targeted therapies for schizophrenia and bipolar disorder.
How similar studies have performed: Previous research has successfully identified genetic risk factors for mental illnesses using similar genomic approaches, indicating a promising avenue for this study.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Roussos, Panagiotis — Icahn School of Medicine at Mount Sinai
- Study coordinator: Roussos, Panagiotis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.