Investigating genetic factors linked to schizophrenia and bipolar disorder

Who could benefit from this research

What this research studies

This research focuses on understanding the genetic and molecular mechanisms behind schizophrenia and bipolar disorder, which are serious mental illnesses affecting many individuals. By analyzing genetic data from diverse populations, the study aims to identify specific genetic variants that contribute to these disorders. The researchers will use advanced techniques to map these variants and explore their functional roles in brain tissue. This comprehensive approach could lead to a better understanding of how these conditions develop and potentially inform future treatments.

Why it matters

Where this research is happening

• Icahn School of Medicine at Mount Sinai
  New York, United States Active

Researchers

• Principal investigator: Roussos, Panagiotis — Icahn School of Medicine at Mount Sinai
• Study coordinator: Roussos, Panagiotis

Related research

Other NIH-funded projects on the same topics.

• Finding genes linked to schizophrenia and bipolar disorder in Latino and mixed-ancestry people

  This project will combine genetic information and gene-activity (RNA) data from Latino people with schizophrenia, bipolar disorder, and people without these conditions to find genes that raise disease risk.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11319730

• Identifying genetic factors for schizophrenia and bipolar disorder in diverse populations

  This study is looking at how genes might play a role in schizophrenia and bipolar disorder specifically in Latino individuals, and it will involve gathering information from 1,500 people, including those with these conditions and healthy individuals, to better understand how genetics can affect mental health and treatm

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11030780

• Investigating how environmental and genetic factors contribute to schizophrenia and bipolar disorder

  This study looks at how things like growing up in a city or facing tough times as a child might affect the chances of developing schizophrenia or bipolar disorder, and how these factors mix with our genes; it's designed to help us find better ways to prevent and treat these conditions.

  NIH research Karolinska Institute · Solna, Sweden · NIH-10577897

• Understanding social disconnection in schizophrenia using digital signals and brain data

  This grant explores how smartphones, social networks, and brain imaging can reveal why Veterans with schizophrenia have trouble forming and maintaining relationships, with the goal of guiding better treatments.

  NIH research VA Greater Los Angeles Healthcare System · Los Angeles, United States · NIH-11615928

• Understanding how autism and schizophrenia risk genes affect brain development

  Scientists are testing how mutations in certain autism and schizophrenia risk genes change brain cells and networks, using patient-derived cells and organoids.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11606500

• Digital support to spread team-based schizophrenia care in primary care in India

  A project to help frontline health workers in India use digital tools to provide coordinated schizophrenia care in primary care, with plans to inform care in the United States as well.

  NIH research Harvard Medical School · Boston, United States · NIH-11580818

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.