Investigating gene fusions and long non-coding RNAs in cancer treatment
Exploring Precision Oncology: From Gene Fusions to lncRNAs
This study is exploring new ways to help people with cancer by using simple tests on urine and blood to find specific genetic clues, which could lead to better diagnoses and treatments tailored just for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10898657 on NIH RePORTER |
What this research studies
This research focuses on advancing precision oncology by identifying molecular targets that can improve the diagnosis and treatment of various cancers. The team at the University of Michigan is developing non-invasive tests that analyze genetic markers in urine and blood to detect prostate cancer and other malignancies. They are also working on innovative therapies that target specific gene fusions associated with cancer progression. By integrating comprehensive genomic sequencing, they aim to provide personalized treatment options for advanced cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients with advanced cancers, particularly those with prostate cancer or other malignancies associated with gene fusions.
Not a fit: Patients with early-stage cancers or those whose cancer does not involve the specific gene fusions being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate cancer diagnoses and targeted therapies, improving patient outcomes.
How similar studies have performed: Previous research has shown success in precision oncology approaches, particularly in the development of non-invasive tests and targeted therapies for cancer.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Chinnaiyan, Arul M — University of Michigan at Ann Arbor
- Study coordinator: Chinnaiyan, Arul M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.