NIH-funded research U01 cooperative agreement

Investigating acute respiratory distress syndrome and its recovery in patients

Official title: Colorado APS Clinical Center

Funded at University of Colorado Denver · NIH-11086039 · Data updated 2026-11-12

This study is looking at how conditions like pneumonia and sepsis can lead to acute respiratory distress syndrome (ARDS) and aims to find out how different factors, like alcohol use and age, affect recovery, so we can improve care and rehabilitation for patients who survive ARDS.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startMay 1, 2023
Project endApril 30, 2029
Funding year2025
Award (this year)$557,182
NIH project number5U01HL168145-03
Project IDNIH-11086039 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with acute respiratory distress syndrome, pneumonia, or sepsis, particularly those with a history of alcohol use disorders.

Less likely to help

Patients with chronic respiratory conditions unrelated to ARDS or those not experiencing acute episodes may not benefit from this research.

What this research studies

This research focuses on understanding acute respiratory distress syndrome (ARDS) and its relationship with conditions like pneumonia and sepsis. It aims to identify specific biological responses in patients that contribute to ARDS and explore how factors such as alcohol use disorders and demographic differences affect outcomes. The study will also examine the recovery process in survivors of ARDS, particularly looking at neuromuscular function and how to improve rehabilitation strategies. By analyzing patient samples and clinical data, the research seeks to enhance diagnosis and treatment approaches for those affected by these serious conditions.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for patients suffering from ARDS and related conditions.

How similar studies have gone: Previous research has shown promising results in understanding ARDS and its associated conditions, indicating that this approach builds on established findings.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Moss, Marc — University of Colorado Denver
  • Study coordinator: Moss, Marc

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.