Investigating a tailored approach to urinary tract infection symptoms in older women

A Randomized Pilot and Feasibility Study of a cultuRE-Directed approach to Urinary traCT Infection symptoms in older womeN: a mixed methods evaluation - the REDUCTION trial

NIH-funded research Magee-Women's Res Inst and Foundation · NIH-10756553

This study is looking at how older women with frequent urinary tract infections can benefit from a new treatment approach that targets the specific bacteria causing their infections, instead of just using standard antibiotics, and it aims to gather their thoughts and experiences to make future treatments better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMagee-Women's Res Inst and Foundation NIH-funded
Lab location1 site (Pittsburgh, UNITED STATES)
Project IDNIH-10756553 on NIH RePORTER

What this research studies

This research focuses on older women who frequently experience urinary tract infections (UTIs), particularly those with recurrent UTIs. It aims to evaluate the feasibility of using a culture-directed treatment strategy compared to standard antibiotic approaches for managing UTI symptoms. The study will involve recruiting participants, assessing their experiences with UTIs, and gathering feedback on the trial design through focus groups and interviews. By understanding patient perspectives and treatment acceptability, the research seeks to improve future recruitment and treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are older women who experience recurrent urinary tract infections and are symptomatic.

Not a fit: Patients who do not have recurrent urinary tract infections or are not experiencing UTI symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatment options for older women suffering from recurrent urinary tract infections.

How similar studies have performed: Previous research has shown promise in using tailored treatment approaches for UTIs, but this specific culture-directed strategy is relatively novel.

Where this research is happening

Pittsburgh, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions bacteria infectionbacterial diseaseBacterial Infections
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.