Investigating a tailored approach to urinary tract infection symptoms in older women
Official title: A Randomized Pilot and Feasibility Study of a cultuRE-Directed approach to Urinary traCT Infection symptoms in older womeN: a mixed methods evaluation - the REDUCTION trial
Funded at Magee-Women's Res Inst and Foundation · NIH-10756553 · Data updated 2026-11-12
This study is looking at how older women with frequent urinary tract infections can benefit from a new treatment approach that targets the specific bacteria causing their infections, instead of just using standard antibiotics, and it aims to gather their thoughts and experiences to make future treatments better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Magee-Women's Res Inst and Foundation NIH-funded |
| Lab location | 1 site (Pittsburgh, UNITED STATES) |
| Project start | January 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $311,517 |
| NIH project number | 5R01DK131273-02 |
| Project ID | NIH-10756553 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older women who experience recurrent urinary tract infections and are symptomatic.
✕Less likely to help
Patients who do not have recurrent urinary tract infections or are not experiencing UTI symptoms may not benefit from this research.
What this research studies
This research focuses on older women who frequently experience urinary tract infections (UTIs), particularly those with recurrent UTIs. It aims to evaluate the feasibility of using a culture-directed treatment strategy compared to standard antibiotic approaches for managing UTI symptoms. The study will involve recruiting participants, assessing their experiences with UTIs, and gathering feedback on the trial design through focus groups and interviews. By understanding patient perspectives and treatment acceptability, the research seeks to improve future recruitment and treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for older women suffering from recurrent urinary tract infections.
How similar studies have gone: Previous research has shown promise in using tailored treatment approaches for UTIs, but this specific culture-directed strategy is relatively novel.
Where this research is happening
-
Magee-Women's Res Inst and Foundation
Pittsburgh, United States Active
Researchers
- Principal investigator: Bradley, Megan — Magee-Women's Res Inst and Foundation
- Study coordinator: Bradley, Megan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.