Investigating a new treatment to prevent preeclampsia during pregnancy
Testing the efficacy of regulatory dendritic cell treatment in the prevention of preeclampsia
['FUNDING_CAREER'] · UNIVERSITY OF MINNESOTA · NIH-10890000
This study is looking at whether giving special immune cells to pregnant people can help prevent preeclampsia, a serious condition that can affect both moms and babies, by improving their immune system and heart health.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-10890000 on ClinicalTrials.gov |
What this research studies
This research explores the use of regulatory dendritic cells as a personalized medicine approach to prevent preeclampsia, a serious pregnancy complication. Preeclampsia is linked to immune dysfunction and can lead to severe health issues for both the mother and baby. The study will involve administering these specialized immune cells to pregnant individuals to see if they can prevent the cardiovascular and immune problems associated with preeclampsia. By understanding how these cells work, the research aims to provide a new preventative strategy for this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant individuals at risk of developing preeclampsia.
Not a fit: Patients who are not pregnant or those who have already developed severe preeclampsia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of preeclampsia, improving outcomes for mothers and their babies.
How similar studies have performed: While the use of regulatory dendritic cells in other immune-mediated diseases has shown promise, this specific application for preeclampsia is novel and untested.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SCROGGINS, SABRINA MARIE — UNIVERSITY OF MINNESOTA
- Study coordinator: SCROGGINS, SABRINA MARIE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases