Interval exercise may improve daily function and heart health for veterans with COPD and sleep apnea

Who could benefit from this research

What this research studies

Veterans with overlapping COPD and obstructive sleep apnea often experience faster functional decline. The study will monitor functional status using the SF-36, daily step counts, and cardiovascular health markers such as CRF, FMD, and hs-CRP to tailor an exercise strategy. By focusing on 3 key domains—participation in daily life, physical activity, and cardiovascular health—the team aims to design an exercise plan that maintains or improves quality of life for OS patients. The research will also consider how excessive daytime sleepiness relates to functional outcomes within the exercise intervention. The goal is to reduce functional decline through increased physical activity tailored to this complex patient group.

Why it matters

Where this research is happening

• Salem VA Medical Center
  Salem, United States Active

Researchers

• Principal investigator: Macrea, Madalina — Salem VA Medical Center
• Study coordinator: Macrea, Madalina

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.