Integrated Microscopy Core Facility supports advanced imaging and molecular analysis
Official title: Integrated Microscopy Core Facility
Funded at University of Wyoming · NIH-11388633 · Data updated 2026-11-12
A dedicated core facility in Wyoming is expanding its advanced imaging and molecular tools to help researchers study the brain and nervous system.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wyoming NIH-funded |
| Lab location | 1 site (Laramie, United States) |
| Project start | September 1, 2017 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $339,324 |
| NIH project number | 5P20GM121310-10 |
| Project ID | NIH-11388633 on NIH RePORTER |
Who could benefit from this research
✓Could help
Researchers and clinicians studying sensory biology, neural circuits, or brain development who need advanced imaging and molecular analysis.
✕Less likely to help
Direct patient participation is not required for core facility activities.
What this research studies
This grant funds a centralized microscopy and molecular analysis core at the University of Wyoming to enhance high-resolution imaging and genome/transcriptome profiling for sensory and nervous system research. It supports both internal SBC labs and external groups, enabling access to state-of-the-art instruments and streamlined workflows. The goal is to increase research productivity, collaborations, and long-term self-sustainability of the core so scientists can uncover how neural circuits develop and function.
Why it matters
Potential benefit: Patients may benefit indirectly through faster discoveries about brain function and sensory biology that could lead to new therapies.
How similar studies have gone: Past CORE expansions have led to higher external funding and productive collaborations affecting neuroscience research.
Where this research is happening
-
University of Wyoming
Laramie, United States Active
Researchers
- Principal investigator: Zhang, Zhaojie — University of Wyoming
- Study coordinator: Zhang, Zhaojie
Related research
Other NIH-funded projects on the same topics.
-
Studying how aging and Alzheimer’s affect the front part of the brain using real-time imaging and computer models
Researchers will combine live brain imaging in animals with computer simulations to understand how aging and Alzheimer’s disease change the prefrontal cortex and relate to memory and thinking problems.
-
Remote AI-guided speech cues to help people with Parkinson’s speak more clearly
A remote AI-based tool uses a web camera to give personalized speech cues to adults with Parkinson’s to improve how clearly they talk.
-
Unlocking biased GPCR signaling to guide safer, smarter drugs
A research program from the University of Wyoming aims to understand how different beta-arrestin proteins shape GPCR signaling to help design drugs with better therapeutic effects and fewer side effects.
-
Ribosomal proteins and pseudogenes in stress-affected neurons
This project looks at how stress changes the proteins that make up ribosomes in brain cells, which could reveal new ways stress affects nervous system health.
-
Impact of early overfeeding on brain hunger neurons and energy balance
This grant looks at how early-life overnutrition may change brain circuits that control hunger and energy use, with potential implications for preventing obesity-related diseases.
-
Exercise timing to reset the brain’s body clock in breast cancer care
A study tests whether exercising at specific times can reset the brain’s circadian clock and potentially improve well-being for people coping with breast cancer.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.