Innovative methods for analyzing individual cells in their spatial context
Pioneering assays for spatially-resolved single-cell multiomics
This study is exploring how cells talk to each other and their surroundings, which is important for figuring out how diseases develop, and it uses a new method to look closely at individual cells and their neighbors to find new ways to treat these conditions.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Survey Genomics, INC. NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-11241688 on NIH RePORTER |
What this research studies
This research focuses on understanding how cells interact and communicate within their environment, which is crucial for uncovering the mechanisms behind various diseases. By using a novel technique called Cytope-drop, researchers can analyze individual cells while also capturing their spatial relationships with neighboring cells. This approach allows for high-throughput analysis of multiple cellular features, such as gene expression and protein presence, without needing extra equipment. The goal is to enhance our understanding of disease progression and potentially identify new therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with advanced diseases or conditions that involve complex cellular interactions, such as cancers or autoimmune disorders.
Not a fit: Patients with isolated or non-complex conditions that do not involve significant cellular communication issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in diagnosing and treating diseases by providing deeper insights into cellular interactions and dysfunctions.
How similar studies have performed: Other research has shown promise in using spatially-resolved single-cell analysis techniques, indicating that this approach could lead to significant advancements in understanding disease mechanisms.
Where this research is happening
Berkeley, United States
- Survey Genomics, INC. — Berkeley, United States (Active)
Researchers
- Principal investigator: Pham, Lin — Survey Genomics, INC.
- Study coordinator: Pham, Lin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.