Infrastructure to study pediatric elbow and wrist fractures with multicenter trials
Official title: IMPACCT: Infrastructure for Musculoskeletal Pediatric Acute Care Clinical Trials
Funded at Lurie Children's Hospital of Chicago · NIH-11320868 · Data updated 2026-11-12
A nationwide network is building the framework to test the best way to treat common elbow and wrist fractures in kids, so doctors can base care on solid evidence.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lurie Children's Hospital of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 1, 2021 |
| Project end | February 28, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,110,417 |
| NIH project number | 5U01AR079113-05 |
| Project ID | NIH-11320868 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children with MEF or DRF who are candidates for either reduction under anesthesia or simple immobilization.
✕Less likely to help
Patients whose injury physiology or needs do not fit the trial criteria or who are not enrolled in the study centers may not benefit from this research.
What this research studies
This project creates a standardized, multicenter setup to run randomized trials comparing reduction under anesthesia versus simple immobilization for pediatric medial epicondyle fractures and displaced distal radius fractures. It brings together 32 centers under the IMPACCT consortium to gain experience and infrastructure for high-quality pediatric orthopedic trials. The effort focuses on reducing unnecessary procedures and anesthesia exposure while ensuring accurate alignment and long-term function. By creating protocols, data collection methods, and regulatory processes, it aims to produce clear, patient-centered guidance for treating these injuries.
Why it matters
Potential benefit: If successful, the research could lead to safer, more effective treatment choices for children with these fractures, reducing anesthesia risks and improving long-term arm function.
How similar studies have gone: There have been few prospective and no randomized studies; this project seeks to provide high-quality evidence where little existed before.
Where this research is happening
-
Lurie Children's Hospital of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Janicki, Joseph a — Lurie Children's Hospital of Chicago
- Study coordinator: Janicki, Joseph a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.