Improving vision recovery in amblyopia through retinal inactivation
Controlling synaptic and intrinsic plasticity underlying visual cortical enhancement
['FUNDING_OTHER'] · GEORGIA INSTITUTE OF TECHNOLOGY · NIH-10850982
This study is looking at how briefly turning off the retinas might help people with amblyopia, a common vision problem, see better by understanding the changes in the brain that happen during recovery, with the hope of finding new ways to improve vision for those affected.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGIA INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-10850982 on ClinicalTrials.gov |
What this research studies
This research investigates how temporary inactivation of the retinas can enhance visual recovery in individuals with amblyopia, a common visual impairment. By studying animal models, the research aims to understand the synaptic and cellular changes that occur in the visual cortex during recovery. The approach focuses on manipulating neural activity patterns to promote better visual outcomes once vision is restored. The ultimate goal is to develop effective treatment strategies that can be applied to improve vision in affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with amblyopia, particularly those who have not yet received effective treatment.
Not a fit: Patients with amblyopia who have already undergone extensive treatment or those with other complicating visual disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment methods that significantly improve vision in patients with amblyopia.
How similar studies have performed: Previous research has shown promising results in using similar approaches to enhance visual recovery in animal models, indicating potential for success in human applications.
Where this research is happening
ATLANTA, UNITED STATES
- GEORGIA INSTITUTE OF TECHNOLOGY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FONG, MING-FAI — GEORGIA INSTITUTE OF TECHNOLOGY
- Study coordinator: FONG, MING-FAI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brain Disorders, Encephalon Diseases, Intracranial CNS Disorders, Intracranial Central Nervous System Disorders, Brain Diseases