Improving ventilation strategies to reduce lung injury in patients with severe respiratory distress

1/2: PREcision VENTilation to attenuate Ventilation-Induced Lung Injury (PREVENT VILI)

NIH-funded research Beth Israel Deaconess Medical Center · NIH-10950466

This study is looking at ways to help people with acute respiratory distress syndrome (ARDS) breathe better while in the hospital, by using special ventilation techniques that are customized for each patient to protect their lungs and improve their recovery.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBeth Israel Deaconess Medical Center NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10950466 on NIH RePORTER

What this research studies

This research focuses on patients suffering from acute respiratory distress syndrome (ARDS), a serious lung condition that often requires intensive care and mechanical ventilation. The study aims to develop and test precise ventilation techniques that can minimize lung injury caused by mechanical ventilation. By tailoring ventilation strategies to individual patient needs, the research seeks to improve outcomes and reduce the long-term effects of ARDS. Patients will be monitored closely to assess the effectiveness of these new approaches.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing acute respiratory distress syndrome.

Not a fit: Patients with chronic respiratory conditions or those not requiring mechanical ventilation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved survival rates and reduced long-term complications for patients with ARDS.

How similar studies have performed: Previous research has shown that tailored ventilation strategies can improve outcomes in patients with similar conditions, indicating a promising approach.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Respiratory Distress SyndromeAdult Respiratory Distress Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.